Jongkyun Kang, Ph.D.
Assistant Professor of Neurology

Education: Korea Advanced Institute of Science and Technology (Ph.D.)

Montenegro P, Chen P, Kang J, Lee SH, Leone S, Shen J. Human Presenilin-1 delivered by AAV9 rescues impaired γ-secretase activity, memory deficits, and neurodegeneration in Psen mutant mice. PNAS 2023, 120(42)
Kang J, Watanabe H, Shen J. Protocols for assessing neurodegenerative phenotypes in Alzheimer’s mouse models. STAR Protocols 2021, 2(3).

Huang G, Bloodgood DW, Kang J, Shahapal A, Chen P, Kaganovsky K, Kim J-I, Ding JB, Shen J. Motor impairments and dopaminergic defects caused by loss of LRRK function in mice. The Journal of Neuroscience 2020, 42(23)

Kang J, Shen J. Cell-autonomous role of presenilin in age-dependent survival of cortical interneurons. Molecular Neurodegeneration 2020, 15 (72).

Lee SH*, Kang J*, Ho A*, Watanabe H, Bolshakov VY, Shen J. APP family regulates neuronal excitability and synaptic plasticity but not neuronal survival. Neuron 2020, 108:676-690. *Co-first author

Kang J, Shin S, Perrimon N, Shen J. An evolutionarily conserved role of Presenilin in neuronal protection in the aging Drosophila brain. Genetics 2017, 206(3), 1479.

Kang J, Yeom E, Lim J Choi KW. Bar represses dPax2 and decapentaplegic to regulate cell fate and morphogenetic cell death in Drosophila eye. PLoS One 2014, 9, e88171.

Kang J, Kim J, Choi KW. Novel cytochrome P450, Cyp6a17, is required for temperature preference behavior in Drosophila. PLoS One 2011, 6, e29800.

Hong ST, Bang S, Hyun S, Kang J, Jeong K, Paik D, Chung J, Kim J. cAMP signalling in mushroom bodies modulates temperature preference behavior in Drosophila. Nature 2008, 454, 771.

Bang S, Hyun S, Hong ST, Kang J, Jeong K, Park JJ, Choe J, Chung J. Dopamine signalling in mushroom bodies regulates temperature-preference behaviour in Drosophila. PLoS Genet 2011, 7, e1001346.

Lee Y, Paik D, Bang S, Kang J, Chun B, Lee S, Bae E, Chung J, Kim J. Loss of spastic paraplegia gene atlastin induces age-dependent death of dopaminergic neurons in Drosophila. Neurobiology of Aging 2006, 29, 84.

Lee Y, Lee Y, Lee J, Bang S, Hyun S, Kang J, Hong S, Bae E, Kaang B, Kim J. Pyrexia is a new thermo-TRP channel endowing tolerance to high temperatures in Drosophila. Nature Genetics 2005, 37, 305.

Hong S, Bang S, Paik D, Kang J, Hwang S, Jeon K, Chun B, Hyun S, Lee Y, Kim J. Histamine and its receptors modulate temperature-preference behavior in Drosophila. Journal of Neuroscience 2006, 26, 7245.

Hyun S, Lee Y, Hong S, Bang S, Paik D, Kang J, Shin J, Lee J, Jeon K, Hwang S, Bae E, Kim J. Drosophila GPCR Han is a receptor for the circadian clock neuropeptide. Neuron 2005, 48, 267.