PUBLICATIONS

2016 – 2020

| < 2000 | 2001 – 2005  |  2006 – 2010  | 2011 – 2015 | 2016 – 2020 | 2021 – 2023 |

Kang J, Shen J. Cell-autonomous role of presenilin in age-dependent survival of cortical interneurons. Molecular Neurodegeneration 2020, 15 (72).

Lee SH, Lutz D, Drexler D, Frotscher M, Shen J. Differential modulation of short-term plasticity at hippocampal mossy fiber and Schaffer collateral synapses by mitochondrial Ca2+. PLOS ONE 2020.

Lee SH, Kang J, Ho A, Watanabe H, Bolshakov VY, Shen J. APP family regulates neuronal excitability and synaptic plasticity but not neuronal survival. Neuron 2020, 108(4): 676-690.

Dhaliwa J, Kannangara TS, Vaculik M, Xue Y, Kumar KL, Maione A, Beique JC, Shen J, Lagace DC. Adult hippocampal neurogenesis occurs in the absence of Presenilin 1 and Presenilin 2. Scientific Reports 2018, 8:17931

Giaime E, Tong Y, Wagner LK, Yuan Y, Huang G, and Shen J (2017). Age-dependent dopaminergic neurodegeneration and impairment of the autophagyk-lysosomal pathway in LRRK-deficient mice. Neuron 2017, 96(4).

Lee SH, Lutz D, Mossalam M, Bolshakov VY, Frotscher M, Shen J. Presenilins regulate synaptic plasticity and mitochondrial calcium homeostasis in the hippocampal mossy fiber pathway. Molecular Neurodegeneration 2017, 12(1): 48.

Wantanabe H and Shen J. Dominant negative mechanism of Presinilin-1 mutations in FAD. Proc Natl Acad Sci USA 2017, 114:12635-12637.

Lee S, Lutz D, Mossalam M, Bolshakov VY, Fortscher M, Shen J. Presenilins regulate synaptic plasticity and mitochondrial calcium homeostasis in the hippocampal mossy fiber pathway. Mol Neurodegen 2017, 12:48.

Kang J, Shin S, Perrimon N, Shen J. An Evolutionarily conserved role of Presenilin in neuronal protection in the aging Drosophila brain. Genetics 2017, 206:1479-1493.

Kelleher RJ and Shen J. Presenilin-1 mutations and Alzheimer’s disease. Proc Natl Acad Sci USA 2017, 114:629-631.

Xia D, Shen J, Kelleher RJ. Loss of A-beta-43 production caused by Presenilin-1 mutations in the knockin mouse brain. Neuron 2016, 90: 417-422.

| < 2000 | 2001 – 2005  |  2006 – 2010  | 2011 – 2015 | 2016 – 2020 | 2021 |

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